3750-36-5 → 2,5-Bis(5-benzyloxycarbonyl-3-ethyl-4-methylpyrrol-2-ylmethyl)-3,4-diethylpyrrole
Reaction equation
[CH2:1]([C:3]1[C:7]([CH2:8][CH3:9])=[CH:6][NH:5][CH:4]=1)[CH3:2].[CH2:10]([O:17][C:18]([C:20]1[NH:21][C:22]([CH2:28]OC(=O)C)=[C:23]([CH2:26][CH3:27])[C:24]=1[CH3:25])=[O:19])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH2:10]([O:17][C:18]([C:20]1[NH:21][C:22]([CH2:28][C:4]2[NH:5][C:6]([CH2:28][C:22]3[NH:21][C:20]([C:18]([O:17][CH2:10][C:11]4[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=4)=[O:19])=[C:24]([CH3:25])[C:23]=3[CH2:26][CH3:27])=[C:7]([CH2:8][CH3:9])[C:3]=2[CH2:1][CH3:2])=[C:23]([CH2:26][CH3:27])[C:24]=1[CH3:25])=[O:19])[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1Participants
3
Procedure
condensing 3,4-diethylpyrrole with two molecular equivalents of benzyl-5-(acetoxymethyl)-4-ethyl-3-methylpyrrole-2-carboxylate to produce 2,5-bis(5-benzyloxycarbonyl-3-ethyl-4-methylpyrrol-2-ylmethyl)-3,4-diethylpyrrole;
Sources & evidence
- ORD record
- ord-f48ec1d5b0004485845e8c5a13588105
- Source dataset
- uspto-grants-1994_04
- Patent number
- US05302714
Reaction notes
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