3,4-Diethylpyrrole → HCID 14541574, compound

HRID 1464019Notes

Reaction equation

HRID 1464019 reaction equation
C(O[CH2:5][C:6]1[NH:10][C:9]([C:11]([O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:12])=[C:8]([CH3:21])[C:7]=1[CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])(=O)C.[CH2:28]([C:30]1[C:34]([CH2:35][CH3:36])=[CH:33][NH:32][CH:31]=1)[CH3:29]>>[CH2:14]([O:13][C:11]([C:9]1[NH:10][C:6]([CH2:5][C:31]2[NH:32][C:33]([CH2:5][C:6]3[NH:10][C:9]([C:11]([O:13][CH2:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=4)=[O:12])=[C:8]([CH3:21])[C:7]=3[CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[C:34]([CH2:35][CH3:36])[C:30]=2[CH2:28][CH3:29])=[C:7]([CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[C:8]=1[CH3:21])=[O:12])[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 109095633,4-DiethylpyrroleHCID 14541573HCID 14541573, compound

Product 1

HCID 14541574HCID 14541574, compound

Procedure

condensing two molecular equivalents of benzyl 5-(acetoxymethyl)-4-ethoxycarbonylmethyl-3-methylpyrrole-2-carboxylate with 3,4-diethyl pyrrole under acidic conditions to produce 2,5-bis(5-benzyloxycarbonyl-3-ethoxycarbonylmethyl-4-methylpyrrol-2-ylmethyl)-3,4-diethylpyrrole;

Sources & evidence

ORD record
ord-484a039bcc5340bf8849bb94fe922a88
Source dataset
uspto-grants-1994_04
Patent number
US05302714

Reaction notes

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