Ammonia → N-(1,1'-Biphenyl)-2-ylthiourea

HRID 1464033Notes

Reaction equation

HRID 1464033 reaction equation
[C:1]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:2]([N:7]=[C:8]=[S:9])=[CH:3][CH:4]=[CH:5][CH:6]=1.[NH3:16]>C(O)C>[C:1]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][C:8]([NH2:16])=[S:9]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 5196591-Isothiocyanato-2-phenylbenzene

Product 1

HCID 1471602N-(1,1'-Biphenyl)-2-ylthiourea

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Treatment of 2-biphenylylisothiocyanate (10.2 g) with a saturated solution of ammonia in ethanol (100 ml) at 10 to 30° for 4 hours and then at 30° C. for 16 hours yielded N-(2-biphenylyl)thiourea (m.p. 183°-184° C.).

Sources & evidence

ORD record
ord-ab8734ebea314a0fa667e2cbcd68a879
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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