3-Methyl-2-nitro-1,1'-biphenyl → 2-amino-3-methylbiphenyl

HRID 1464053Notes

Reaction equation

HRID 1464053 reaction equation
[CH3:1][C:2]1[C:3]([N+:14]([O-])=O)=[C:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1>C(O)C>[NH2:14][C:3]1[C:2]([CH3:1])=[CH:7][CH:6]=[CH:5][C:4]=1[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

Participants

3

Reactant 1

HCID 140439853-Methyl-2-nitro-1,1'-biphenyl

Product 1

HCID 6030842-amino-3-methylbiphenyl

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3-Methyl-2-nitrobiphenyl (1 g) was heated at 90°-95° C. for 28 hours with hydrated sodium sulphide (4.5 g) and ethanol (25 ml) to give 2-amino-3-methyl-biphenyl (m.p. 66°-67° C.) which was recrystallised from hexane and converted into its hydrochloride salt.

Sources & evidence

ORD record
ord-bdd1efac89e8405f93c262c00a09324e
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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