反应详情

A mixture of 2-amino-5-fluorobiphenyl hydrochloride (3.6 g), N,N-dimethylcyanamide (1.68 g) and m-cresol (25 ml) was heated at 90°-95° C. for 8 hours to give N-(5-fluoro-2-biphenylyl)-N',N'-dimethylguanidine (m.p. 160°-161° C.) which was recrystallised from hexane.

1. temperaturewas heated at 90°-95° C. for 8 hours