反应详情

A suspension of N-(2-biphenylyl)thiourea (7.8 g) in water (60 ml) was reacted with a solution of potassium hydroxide (19.15 g) in water (60 ml), lead acetate trihydrate (12.96) in water (60 ml) was added and the reaction mixture heated at 90°-95° C. for 30 minutes and filtered. The filtrate was acidified with acetic acid with cooling to yield 2-biphenylylcyanamide as a colourless solid (m.p. 85°-87° C.).

1. additionwas added
2. temperaturethe reaction mixture heated at 90°-95° C. for 30 minutes
3. filtrationfiltered
4. temperaturewith cooling