Ammonia → HCID 19089278, compound

HRID 1464074Notes

Reaction equation

HRID 1464074 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([N:14]=[C:15]=[S:16])[C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:6][CH:7]=1.[NH3:17]>C(O)C>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[C:4]([NH:14][C:15]([NH2:17])=[S:16])[CH:3]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 19089174HCID 19089174, compound

Product 1

HCID 19089278HCID 19089278, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 4-fluoro-2-biphenylylisothiocyanate (12 g) in ethanol (10 ml) with 25% aqueous ammonia solution (40 ml) at ambient temperature for 8 hours gave N-(4-fluoro-2-biphenylyl)thiourea as a white solid (m.p. 185°-187° C.).

Sources & evidence

ORD record
ord-25eea66ade2943a79300aebcbbcdfc82
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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