HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophosgene → 5-Fluoro-2-biphenylylisothiocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophosgene | HCID 10040 | — |
| Reactant | 4-Fluoro-2-phenylaniline | HCID 19089219 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-Fluoro-2-biphenylylisothiocyanate | HCID 19089275 | — |
Reaction Steps
Reaction of 2-amino-5-fluorobiphenyl (7.8 g) with thiophosgene (7.2 g) in a mixture of dioxan (15 ml) and water (60 ml) at ambient temperature for 2 hours yielded 5-fluoro-2-biphenylylisothiocyanate as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05302720 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-e1352bff720d49a485c8be120371db65 |
| Source note | uspto-grants-1994_04 |