HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophosgene → 5-Methyl-2-biphenylylisothiocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophosgene | HCID 10040 | — |
| Reactant | 4-Methyl-2-phenylaniline | HCID 4712165 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-Methyl-2-biphenylylisothiocyanate | HCID 19089206 | — |
Reaction Steps
Reaction of 2-amino-5-methylbiphenyl (7 g) with thiophosgene (5.7 g) in a mixture of dioxan (20 ml) and water (50 ml) at 0°-5° C. for 30 minutes and at ambient temperature for 1 hour gave 5-methyl-2-biphenylyl isothiocyanate as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05302720 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-64ffec76d3064595a6440cadaf774fe3 |
| Source note | uspto-grants-1994_04 |