Ammonia → N-(5-methyl-2-biphenylyl)thiourea

HRID 1464080Notes

Reaction equation

HRID 1464080 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5]([N:14]=[C:15]=[S:16])=[CH:4][CH:3]=1.[NH3:17]>C(O)C>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([NH:14][C:15]([NH2:17])=[S:16])=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:7]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 190892065-Methyl-2-biphenylylisothiocyanate

Product 1

HCID 19089313N-(5-methyl-2-biphenylyl)thiourea

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 5-methyl-2-biphenylylisothiocyanate (7.5 g) in ethanol (20 ml) with 25% aqueous ammonia solution (60 ml) at ambient temperature for 2 hours yielded N-(5-methyl-2-biphenylyl)thiourea as a colourless solid (m.p. 175°-177° C.).

Sources & evidence

ORD record
ord-6fce3a5c01204c47a678da2dfd07a51c
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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