Ammonia → N-(4-methylthio-2-biphenylyl)thiourea

HRID 1464085Notes

Reaction equation

HRID 1464085 reaction equation
[CH3:1][S:2][C:3]1[CH:4]=[C:5]([N:15]=[C:16]=[S:17])[C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:7][CH:8]=1.[NH3:18]>C(O)C>[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[C:5]([NH:15][C:16]([NH2:18])=[S:17])[CH:4]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 190892824-Methylthio-2-biphenylylisothiocyanate

Product 1

HCID 19089234N-(4-methylthio-2-biphenylyl)thiourea

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 4-methylthio-2-biphenylylisothiocyanate (11.5 g), ethanol (100 ml) and 25% aqueous ammonia solution (20 ml) at ambient temperature for 15 hours gave N-(4-methylthio-2-biphenylyl)thiourea as a colourless solid (m.p. 166°-167° C.).

Sources & evidence

ORD record
ord-66b532896c204aeaa9f6269f7d25f9c8
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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