Potassium Hydroxide → 4-Methylthio-2-biphenylylcyanamide

HRID 1464086Notes

Reaction equation

HRID 1464086 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[C:5]([NH:15][C:16]([NH2:18])=S)[CH:4]=1.[OH-].[K+].O.O.O.C([O-])(=O)C.[Pb+2].C([O-])(=O)C>O>[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[C:5]([NH:15][C:16]#[N:18])[CH:4]=1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 22456Lead diacetate trihydrateHCID 19089234N-(4-methylthio-2-biphenylyl)thiourea

Product 1

HCID 190892674-Methylthio-2-biphenylylcyanamide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of N-(4-methylthio-2-biphenylyl)thiourea (9.6 g), potassium hydroxide (8.5 g), lead acetate trihydrate (12.5 g) and water (165 ml) was heated at 90°-95° C. for 30 minutes to give 4-methylthio-2-biphenylylcyanamide.

Workup

  1. temperaturewas heated at 90°-95° C. for 30 minutes

Sources & evidence

ORD record
ord-8912914b9c024cf7b1e2f4aef4b2905a
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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