Ammonia → N-(4'-chloro-2-biphenylyl)thiourea

HRID 1464097Notes

Reaction equation

HRID 1464097 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([N:14]=[C:15]=[S:16])=[CH:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.[NH3:17]>C(O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[NH:14][C:15]([NH2:17])=[S:16])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 190892634'-Chloro-2-biphenylylisothiocyanate

Product 1

HCID 15175541N-(4'-chloro-2-biphenylyl)thiourea

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 4'-chloro-2-biphenylylisothiocyanate (7.6 g) with ethanol (100 ml) with 25% aqueous ammonia solution (15 ml) for 18 hours at ambient temperature yielded N-(4'-chloro-2-biphenylyl)thiourea (m.p. 175°-177° C.).

Sources & evidence

ORD record
ord-fa3fdc7c298a4a4088d3d65843435563
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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