Sodium Hydroxide → HCID 15175511, compound

HRID 1464100Notes

Reaction equation

HRID 1464100 reaction equation
C([NH:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[C:19]1[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=1)=[S:11])(=O)C1C=CC=CC=1.[OH-].[Na+]>O>[F:25][C:22]1[CH:21]=[CH:20][C:19]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[NH:12][C:10]([NH2:9])=[S:11])=[CH:24][CH:23]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 15175510N-benzoyl-N'-(4'-fluoro-2-biphenylyl)thiourea

Product 1

HCID 15175511HCID 15175511, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of N-benzoyl-N'-(4'-fluoro-2-biphenylyl)thiourea (2.8 g) and sodium hydroxide (0.4 g) and water (10 ml) was heated at 90°-95° C. for 8 hours to yield N-(4'-fluoro-2-biphenylyl)thiourea as a colourless solid (m.p. 140°-142° C.).

Workup

  1. temperaturewas heated at 90°-95° C. for 8 hours

Sources & evidence

ORD record
ord-93e06ed1f3a6484894633508b0645ce7
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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