Potassium Hydroxide → HCID 19089180, compound

HRID 1464101Notes

Reaction equation

HRID 1464101 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[NH:14][C:15]([NH2:17])=S)=[CH:4][CH:3]=1.O.O.O.C([O-])(=O)C.[Pb+2].C([O-])(=O)C.[OH-].[K+]>O>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[NH:14][C:15]#[N:17])=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 22456Lead diacetate trihydrateHCID 15175511HCID 15175511, compound

Product 1

HCID 19089180HCID 19089180, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of N-(4'-fluoro-2-biphenylyl)thiourea (1.4 g), lead acetate trihydrate (2.15 g) and potassium hydroxide (3.18 g) in water (60 ml) was heated at 90°-95° C. for 1 hour to yield 4'-fluoro-2-biphenylylcyanamide as a colourless solid (m.p. 95°-96° C.).

Workup

  1. temperaturewas heated at 90°-95° C. for 1 hour

Sources & evidence

ORD record
ord-6e1c13a569c54d25adad76949f26d846
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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