Sodium Hydroxide → HCID 15175538, compound

HRID 1464104Notes

Reaction equation

HRID 1464104 reaction equation
C([NH:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[F:25])=[S:11])(=O)C1C=CC=CC=1.[OH-].[Na+]>O>[F:25][C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=1[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=1[NH:12][C:10]([NH2:9])=[S:11]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 15175521HCID 15175521, compound

Product 1

HCID 15175538HCID 15175538, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of N-benzoyl-N'-(2'-fluoro-2-biphenylyl)thiourea (9.5 g), sodium hydroxide (1.14 g) and water (80 ml) was heated at 90°-95° C. for 8 hours to give N-(2'-fluoro-2-biphenylyl)thiourea as a colourless solid (m.p. 175°-177° C.).

Workup

  1. temperaturewas heated at 90°-95° C. for 8 hours

Sources & evidence

ORD record
ord-26a8143a2bef4ac29f3a101b8f63e732
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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