HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidin-4-ol → HCID 178511979, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidin-4-ol | HCID 79341 | — |
| Reactant | HCID 19089315 | HCID 19089315 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 178511979 | HCID 178511979 | — |
Reaction Steps
A mixture of 3'-fluoro-2-biphenylylcyanamide (4.1 g) and 4-hydroxypiperidine (1.95 g) in 1,2-dimethoxyethane (30 ml) was heated at 90°-95° C. for 4 hours to give N-(3'-fluoro-2-biphenylyl)-4-hydroxypiperidine-1-carboxamidine as a colourless solid (m.p. 147°-148° C.) which was recrystallised from ethylacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05302720 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-e4cbedaf088e4773a031a9f9c95d99f3 |
| Source note | uspto-grants-1994_04 |