Thiophosgene → HCID 19089253, compound

HRID 1464115Notes

Reaction equation

HRID 1464115 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1.[C:16](Cl)(Cl)=[S:17]>O1CCOCC1.O>[CH3:15][O:14][C:11]1[CH:12]=[CH:13][C:8]([C:3]2[C:2]([N:1]=[C:16]=[S:17])=[CH:7][CH:6]=[CH:5][CH:4]=2)=[CH:9][CH:10]=1

Participants

5

Reactant 2

HCID 10040ThiophosgeneHCID 27595624'-Methoxy[1,1'-biphenyl]-2-amine

Product 1

HCID 19089253HCID 19089253, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 312751,4-DioxaneSolvent

Procedure

Reaction of 2-amino-4'-methoxybiphenyl (10 g) with thiophosgene (8.7 g) in dioxane (25 ml) and water (80 ml) at 0° C. for 3 hours gave 4'-methoxy-2-biphenylylisothiocyanate as a pale yellow oil.

Sources & evidence

ORD record
ord-e7127db33d954f6bb9d1a2d3cb176d14
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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