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HRID1464124

反应详情

EQUATION

反应方程式

HRID 1464124 的结构方程式

REACTANTS

反应物

3
结构：O=C=Nc1ccc(Cl)cc1
HCID7693

4-Chlorophenyl isocyanate

C7H4ClNO

结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：NS(=O)(=O)c1cccs1
HCID72881

2-Thiophenesulfonamide

C4H5NO2S2

PRODUCTS

生成物

1
结构：O=C(Nc1ccc(Cl)cc1)NS(=O)(=O)c1cccs1
HCID15669317

N-[(4-Chlorophenyl)carbamoyl]thiophene-2-sulfonamide

C11H9ClN2O3S2

收率 85%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

2 次

PROCEDURE

实验过程

The procedure of Example 4B was followed with 2-thiophenesulfonamide (4.2 g, 26 mmole) in 40 ml of acetone, 1N NaOH (26 ml, 26 mmole) and 4-chlorophenyl isocyanate (4.0 g, 26 mmole) in 40 ml of acetone. 7 g of named product were obtained