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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464127Generated: October 25, 2026

3-Methylthiophene → 3-Methylthiophene-2-sulfonamide

https://huagongshe.com/reaction/1464127

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylthiopheneHCID 12024—
ReactantAmmonium HydroxideHCID 14923—
ReactantChlorosulfonic acidHCID 24638—
SolventChloroformHCID 6212—
Product3-Methylthiophene-2-sulfonamideHCID 341083—

Reaction Steps

The procedure of Example 3A was followed with 3-methylthiophene (10.0 g, 102 mmole), chlorosulfonic acid (29.58 g, 255 mmoles) in chloroform (200 ml), concentrated ammonium hydroxide, to provide 3-methyl-2-thiophenesulfonamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05302724
Source datasetuspto-grants-1994_04
ORD IDord-5c67b8fc142f4e7480be130afff425bf
Source noteuspto-grants-1994_04