Ethane, 2-bromo-1,1-diethoxy- → HCID 15713981, compound

Participants

Reaction Steps

To a solution containing potassium t-butoxide (5.91 g), methyl 4-oxo-3H-phthalazin-1-ylacetate (10.91 g) and DMF (50 ml) was added bromoacetaldehyde diethylacetal (10.83 g), and the reaction mixture was allowed to stir at room temperature for 48 hours. The reaction mixture was poured onto water, extracted with ethyl acetate and the ethyl acetate layer was collected and dried. Upon evaporation of the solvent, a clear oil was obtained which upon standing gave a white solid (yield, 5.2 g; m.p. 68° C.).

Provenance & Evidence