Hydrogen Bromide → HCID 19087649, compound

Participants

Reaction Steps

A mixture of 1-[4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)butyl]-7-methoxy-2,4(1H,3H)-quinazolinedione (300 mg) and 47% hydrobromic acid (3.8 ml) in acetic acid (6 ml) was refluxed for 24 hours. After dilution with water, precipitates were collected. A crude crystalline material was recrystallized from ethanol to give 1-[4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)butyl]-7-hydroxy-2,4(1H,3H)-quinazolinedione hydrobromide (140 mg).

Provenance & Evidence