HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Dimethylaminopyridine → 2-[3-Bromo-4-(quinolin-2-yl-methoxy)phenyl]acetylmethanesulphonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Dimethylaminopyridine | HCID 21885 | — |
| Reactant | Methanesulfonamide | HCID 72879 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | 2-[3-Bromo-4-(quinolin-2-yl-methoxy)phenyl]acetic acid | HCID 19087785 | — |
| Product | 2-[3-Bromo-4-(quinolin-2-yl-methoxy)phenyl]acetylmethanesulphonamide | HCID 19087778 | — |
Reaction Steps
In anology to the procedure of Example XVI, the title compound is prepared from 2.8 g (7.5 mmol) of the compound from Example XXI, 0.71 g (7.5 mmol) of dried methanesulphonamide, 1.44 g (7.5 mmol) of N-ethyl-N'-dimethylaminopropylcarbodiimide hydrochloride and 0.92 g (7.5 mmol) of dimethylaminopyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05304563 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-c862680919a641f0b40daec025283d28 |
| Source note | uspto-grants-1994_04 |