Sodium Hydroxide → 2-[3-Vinyl-4-(quinolin-2-yl-methoxy)phenyl]acetic acid

HRID 1464391Notes

Reaction equation

HRID 1464391 reaction equation
[CH:1]([C:3]1[CH:4]=[C:5]([CH2:21][C:22]([O:24]C)=[O:23])[CH:6]=[CH:7][C:8]=1[O:9][CH2:10][C:11]1[CH:20]=[CH:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=1)=[CH2:2].[OH-].[Na+]>>[CH:1]([C:3]1[CH:4]=[C:5]([CH2:21][C:22]([OH:24])=[O:23])[CH:6]=[CH:7][C:8]=1[O:9][CH2:10][C:11]1[CH:20]=[CH:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=1)=[CH2:2]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 19087790Methyl 2-[3-vinyl-4-(quinolin-2-yl-methoxy)phenyl]acetate

Product 1

HCID 190877712-[3-Vinyl-4-(quinolin-2-yl-methoxy)phenyl]acetic acid

Procedure

In analogy to the procedure of Example XV, the title compound is prepared from 1.1 g (3.3 mmol) of the compound from Example XXXII and 5 ml (5 mmol) of 1N sodium hydroxide solution.

Sources & evidence

ORD record
ord-03229cd1443b46b9b8e2594b30940e4e
Source dataset
uspto-grants-1994_04
Patent number
US05304563

Reaction notes

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