Methyl 2-[3-vinyl-4-(quinolin-2-yl-methoxy)phenyl]acetate → Methyl 2-[3-ethyl-4-(quinolin-2-yl-methoxy)phenyl]acetate

Participants

Reaction Steps

14.3 g (0.0429 mol) of the compound from Example XXXII are dissolved in 150 ml of methanol and 15 ml of glacial acetic acid, 1.5 g of 5% strength Pd-C are added, and the reaction mixture is heated to 30°-35° C. and hydrogenated. It is filtered through silica gel, the filtrate is concentrated in vacuo and the residue is recrystallised from isopropanol.

Provenance & Evidence