Sodium Hydroxide → 2-[3-Ethyl-4-(quinolin-2-yl-methoxy)phenyl]acetic acid

HRID 1464393Notes

Reaction equation

HRID 1464393 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]([CH2:21][C:22]([O:24]C)=[O:23])[CH:6]=[CH:7][C:8]=1[O:9][CH2:10][C:11]1[CH:20]=[CH:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=1)[CH3:2].[OH-].[Na+]>>[CH2:1]([C:3]1[CH:4]=[C:5]([CH2:21][C:22]([OH:24])=[O:23])[CH:6]=[CH:7][C:8]=1[O:9][CH2:10][C:11]1[CH:20]=[CH:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=1)[CH3:2]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 19087796Methyl 2-[3-ethyl-4-(quinolin-2-yl-methoxy)phenyl]acetate

Product 1

HCID 190877752-[3-Ethyl-4-(quinolin-2-yl-methoxy)phenyl]acetic acid

Procedure

The title compound is prepared from 1.5 g (4.48 mmol) of the compound from Example XXXIV and 10 ml (10 mmol) of 1N sodium hydroxide solution analogously to the procedure of Example V.

Sources & evidence

ORD record
ord-1ffabec3f635496da78864f9126656ca
Source dataset
uspto-grants-1994_04
Patent number
US05304563

Reaction notes

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