HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Dimethylaminopyridine → N-[3-Ethyl-4-(quinolin-2-yl-methoxy)phenyl]acetylmethanesulphonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Dimethylaminopyridine | HCID 21885 | — |
| Reactant | Methanesulfonamide | HCID 72879 | — |
| Reactant | 2-[3-Ethyl-4-(quinolin-2-yl-methoxy)phenyl]acetic acid | HCID 19087775 | — |
| Reactant | 1-(3-Dimethylaminopropyl)-3-methylcarbodiimide hydrochloride | HCID 19608651 | — |
| Product | N-[3-Ethyl-4-(quinolin-2-yl-methoxy)phenyl]acetylmethanesulphonamide | HCID 19087800 | — |
Reaction Steps
Analogously to the procedure of Example XVI, the title compound is prepared from 1.7 g (5.3 mmol) of the compound from Example XXXV, 0.6 g (6 mmol) of methanesulphonamide, 1.2 g (6 mmol) of N-methyl-N'-dimethylaminopropylcarbodiimide hydrochloride and 0.8 g (6 mmol) of dimethylaminopyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05304563 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-e07d37890a13443bbf4aa7f45a6f0de2 |
| Source note | uspto-grants-1994_04 |