Bromocycloheptane → HCID 19025754, compound

HRID 1464402Notes

Reaction equation

[CH2:1]([C:5]1[CH:6]=[C:7]([CH2:23][C:24]([O:26][CH3:27])=[O:25])[CH:8]=[CH:9][C:10]=1[O:11][CH2:12][C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:14]=1)[CH:2]([CH3:4])[CH3:3].[CH:28]1(Br)[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[CH2:1]([C:5]1[CH:6]=[C:7]([CH:23]([CH:28]2[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]2)[C:24]([O:26][CH3:27])=[O:25])[CH:8]=[CH:9][C:10]=1[O:11][CH2:12][C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:14]=1)[CH:2]([CH3:4])[CH3:3]

Participants

Reactant 2

HCID 16992Bromocycloheptane

HCID 19087768HCID 19087768, compound

Product 1

HCID 19025754HCID 19025754, compound

Procedure

10 g (0.0275 mol) of methyl 2-[3-isobutyl-4-(quinolin-2-yl-methoxy)phenyl]acetate are reacted, in analogy to the procedure of Example 1, with 10.04 g (0.055 mol) of cycloheptyl bromide and 6.17 g (0.055 mol) of potassium tertiary butylate to give the title compound.

Sources & evidence

ORD record: ord-706453dfe39c49f1b3ac700c106de5ae
Source dataset: uspto-grants-1994_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05304563

Reaction notes

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