Thionyl Chloride → Benzo[b]thiophene-2-carbonyl Chloride

HRID 1464426Notes

Reaction equation

HRID 1464426 reaction equation
[S:1]1[C:5]([C:6](O)=[O:7])=[CH:4][C:3]2[CH:9]=[CH:10][CH:11]=[CH:12][C:2]1=2.S(Cl)([Cl:15])=O>>[S:1]1[C:5]([C:6]([Cl:15])=[O:7])=[CH:4][C:3]2[CH:9]=[CH:10][CH:11]=[CH:12][C:2]1=2

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 95864Benzo(b)thiophene-2-carboxylic acid

Product 1

HCID 142384Benzo[b]thiophene-2-carbonyl Chloride

Procedure

1.0 g of benzo[b]thiophene-2-carboxylic acid was reacted with 2 ml of thionyl chloride under reflux overnight, and then excess thionyl chloride was distilled off under reduced pressure to obtain benzo[b]thiophene-2-carbonyl chloride as a solid product.

Workup

  1. temperatureunder reflux overnight
  2. distillationexcess thionyl chloride was distilled off under reduced pressure

Sources & evidence

ORD record
ord-c1d2b30627914f50aac0cc15ae272f3c
Source dataset
uspto-grants-1994_04
Patent number
US05304657

Reaction notes

Loading…