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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464455Generated: October 31, 2026

L-Aspartic Acid → Aspartame

https://huagongshe.com/reaction/1464455

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Aspartic AcidHCID 5960—
ReactantL-PhenylalanineHCID 6140—
ReactantAspartameHCID 134601—
ProductAspartameHCID 134601—
ProductL-Phenylalanine, methyl esterHCID 736234—
ProductN-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamideHCID 11298025—

Reaction Steps

A method according to claim 1 wherein α-L-aspartyl-L-phenylalanine methyl ester, L-phenylalanine and L-aspartic acid are recovered from solutions formed in the preparation of α-L-aspartyl-L-phenylalanine methyl ester using, as raw materials, N-formyl-L-aspartic anhydride and L-phenylalanine methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05304671
Source datasetuspto-grants-1994_04
ORD IDord-7dfd2e6592194ae896b9929b40833598
Source noteuspto-grants-1994_04