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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464712Generated: October 31, 2026

o-Cumenyl chloroformate → Benzene, 1-chloro-2-(1-methylethyl)-

https://huagongshe.com/reaction/1464712

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-Cumenyl chloroformateHCID 6365464—
ReactantAluminum(III) ChlorideHCID 6451240—
ProductBenzene, 1-chloro-2-(1-methylethyl)-HCID 1637720%

Reaction Conditions

Temperature200 °C

Reaction Steps

0.35 g of anhydrous aluminium chloride was added to 25 g of 2-isopropylphenyl chloroformate and the mixture was heated at 200° C. for 3 hours at normal pressure. The reaction mixture was cooled and worked up as described in Example 1. 2-Isopropylchlorobenzene was obtained in a yield of 20%, which is considerable despite the unfavourable substitution pattern.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05306849
Source datasetuspto-grants-1994_04
ORD IDord-0c4624d1938140769baec1ebe948d82c
Source noteuspto-grants-1994_04