HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Hydroxymethyl)furfural → 2-Furanmethanol, 5-(dimethoxymethyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Hydroxymethyl)furfural | HCID 237332 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Methylorthoformate | HCID 53629101 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Furanmethanol, 5-(dimethoxymethyl)- | HCID 588127 | — |
Reaction Steps
16.8 g of 5-hydroxymethyl-2-furaldehyde was dissolved in 70 ml of methanol, and 14.7 ml of methyl orthoformate and 170 mg of pyridinium p-toluenesulfonate were added. After the mixture was stirred at room temperature for 2 hours, 350 mg of sodium bicarbonate was added . The solution was stirred at room temperature for 30 minutes, and then ethyl ether and water were added. The organic layer separated was worked up in a customary manner to give 21.6 g of 5-hydroxymethyl-2-furaldehyde dimethylacetal as a pale brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05306728 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-5b47d8919a65412297a660ee84b31f52 |
| Source note | uspto-grants-1994_04 |