Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 19916952 | HCID 19916952 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 19917075 | HCID 19917075 | 46.3% |
Reaction Steps
0.65 g of 3-[3-(5-bromopentyloxy)phenyl]thiophene, 0.37 g of potassium phthalimide and 0.14 g of potassium carbonate were dissolved in 5 ml of dimethylformamide, and the mixture was heated at 50° C. with stirring for 5 hours. Ethyl acetate and water were added, and the organic layer separated was worked up in a customary manner. The product was purified by silica gel column chromatography [hexane / ethyl acetate=7/1 →5/1] to give 0.36 g of N-[5-[3-(3-thienyl)phenoxy]pentyl] phthalimide as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05306728 |
|---|
| Source dataset | uspto-grants-1994_04 |
|---|
| ORD ID | ord-a969e4247e69454f8a36d3aa81551a70 |
|---|
| Source note | uspto-grants-1994_04 |
|---|
