Water → HCID 309016, compound

Participants

Reaction Steps

0.57 g of potassium phthlimide was suspended in 20 ml of dimethylformamide, and 2.42 g of α,α-dibromo-m-xylene was added. The mixture was stirred overnight at room temperature, and then ethyl ether and water were added. The organic layer separated was worked up in a customary manner, and the product was purified by silica gel column chromatography [hexane / ethyl acetate=10/1] to give 0.52 g of N-(3-bromomethylbenzyl)phthalimide as a white crystalline powder.

Provenance & Evidence