HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → (E)-3-(N-ethyl-6,6-dimethyl-2-hepten-4-ynylaminomethyl) cinnamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 5-(Hydroxymethyl)furfural | HCID 237332 | — |
| Reactant | 3-(Hydroxymethyl)benzaldehyde | HCID 13131455 | — |
| Reactant | (E)-N-ethyl-6,6-dimethyl-2-hepten-4-ynylamine hydrochloride | HCID 19917114 | — |
| Reactant | (E)-N-ethyl-6-methoxy-6-methyl-2-hepten-4-ynylamine hydrochloride | HCID 19917137 | — |
| Reactant | ethyl (E)-3-(N-ethyl-6,6-dimethyl-2-hepten-4-ynylaminomethyl)cinnamate | HCID 86747792 | — |
| Product | (E)-3-(N-ethyl-6,6-dimethyl-2-hepten-4-ynylaminomethyl) cinnamic acid | HCID 86747791 | — |
Reaction Steps
When ethyl (E)-3-(N-ethyl-6,6-dimethyl-2-hepten-4-ynylaminomethyl)cinnamate, prepared by using 3-hydroxymethylbenzaldehyde and (E)-N-ethyl-6,6-dimethyl-2-hepten-4-ynylamine hydrochloride instead of the starting 5-hydroxymethyl-2-furaldehyde and (E)-N-ethyl-6-methoxy-6-methyl-2-hepten-4-ynylamine hydrochloride as in Referential Example 46, is hydrolyzed with potassium hydroxide, (E)-3-(N-ethyl-6,6-dimethyl-2-hepten-4-ynylaminomethyl) cinnamic acid is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05306728 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-9367b6f21e454c158e26a5a1fff13a24 |
| Source note | uspto-grants-1994_04 |