Methanol → 4-Methylamino-3-ethyl-3-methylpiperidine

HRID 146481Notes

Reaction equation

HRID 146481 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10]([CH3:16])([CH2:17][CH3:18])[CH:11]([NH:14][CH3:15])[CH2:12][CH2:13]1.[CH3:19][OH:20].[H:21][H:22].[OH-:23].[OH-:24].[Pd+2:25]>>[NH:8]1[CH2:9][C:10]([CH3:16])([CH2:17][CH3:18])[CH:11]([NH:14][CH3:15])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 22278853HCID 22278853, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 222788634-Methylamino-3-ethyl-3-methylpiperidine

Sources & evidence

ORD record
ord-e60d0b4d06d24ddeac921656a24aa6d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…