Triethyl phosphite → HCID 59601718, compound

HRID 1464862Notes

Reaction equation

HRID 1464862 reaction equation
[CH:1]([O:3][C:4](Cl)=[O:5])=[CH2:2].[P:7]([O:14]CC)([O:11][CH2:12][CH3:13])[O:8][CH2:9][CH3:10]>>[CH2:9]([O:8][P:7]([C:4]([O:3][CH:1]=[CH2:2])=[O:5])(=[O:14])[O:11][CH2:12][CH3:13])[CH3:10]

Participants

3

Reactant 2

HCID 31215Triethyl phosphiteHCID 78808Vinyl chloroformate

Product 1

HCID 59601718HCID 59601718, compound

Conditions

Temperature
0 °C

Procedure

2.0 g (19 mmol) of chloroformic acid vinyl ester were precharged into a 50 ml two-necked flask, and, while stirring at 0° C., 3.13 g (19 mmol) of triethyl phosphite were slowly added dropwise. After completion of the addition, the reaction mixture was stirred for further 2 hours at room temperature. For complete removal of the ethyl chloride formed during the reaction, the solution was heated to 40° C. for 30 minutes. Purification by vacuum destillation yielded 2.5 g (64% of th.) of the title compound as a colorless liquid.

Workup

  1. additionAfter completion of the addition
  2. stirringthe reaction mixture was stirred for further 2 hours at room temperature
  3. customFor complete removal of the ethyl chloride
  4. customformed during the reaction
  5. temperaturethe solution was heated to 40° C. for 30 minutes
  6. customPurification by vacuum destillation

Sources & evidence

ORD record
ord-b899b364a99e4587b4d92ddc37db41c7
Source dataset
uspto-grants-2015_04
Patent number
US08999323B2

Reaction notes

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