HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-fluoro-1-methyl-3-difluoromethyl-1H-pyrazole-4-carbonyl chloride → HCID 86679338, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-fluoro-1-methyl-3-difluoromethyl-1H-pyrazole-4-carbonyl chloride | HCID 52920508 | — |
| Reactant | HCID 64506015 | HCID 64506015 | — |
| Product | HCID 86679338 | HCID 86679338 | 54% |
Reaction Steps
As for example 1—step 6, condensation of 0.50 g 3-(3,3-dimethylbutyl)cyclohexanamine over 0.638 g of 3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carbonyl chloride gives 0.65 (54% of theory) of 3-(difluoromethyl)-N-[3-(3,3-dimethylbutyl)cyclohexyl]-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide. log P=4.80.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999956B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-a6a464bc15c64a77bc0deb519121c184 |
| Source note | uspto-grants-2015_04 |