(1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptane → HCID 66747727, compound

HRID 1464956Notes

Reaction equation

HRID 1464956 reaction equation
[C@H:1]12[CH2:7][C@H:4]([NH:5][CH2:6]1)[CH2:3][N:2]2[C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9].Cl[C:16]1[CH:21]=[C:20]([O:22][CH2:23][CH:24]([CH3:26])[CH3:25])[N:19]=[CH:18][N:17]=1>>[CH2:23]([O:22][C:20]1[N:19]=[CH:18][N:17]=[C:16]([N:5]2[CH2:6][C@@H:1]3[CH2:7][C@H:4]2[CH2:3][N:2]3[C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[CH:21]=1)[CH:24]([CH3:26])[CH3:25]

Participants

3

Reactant 2

HCID 11521263(1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptaneHCID 61278956HCID 61278956, compound

Product 1

HCID 66747727HCID 66747727, compound

Procedure

The title compound was prepared according to the procedure described in Step-1 of Intermediate C using tert-butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate and 4-chloro-6-isobutoxypyrimidine.

Sources & evidence

ORD record
ord-090c5163a28c469dbd945af8ce313503
Source dataset
uspto-grants-2015_04
Patent number
US08999974B2

Reaction notes

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