4-Fluorobenzoic Acid → HCID 56654151, compound

HRID 1464967Notes

Reaction equation

HRID 1464967 reaction equation
Cl.Cl.[NH2:3][CH2:4][C:5]([N:7]1[CH2:12][CH2:11][N:10]([C:13]2[CH:18]=[C:17]([O:19][CH2:20][CH:21]([CH3:23])[CH3:22])[N:16]=[CH:15][N:14]=2)[CH2:9][CH2:8]1)=[O:6].[F:24][C:25]1[CH:33]=[CH:32][C:28]([C:29](O)=[O:30])=[CH:27][CH:26]=1>>[F:24][C:25]1[CH:33]=[CH:32][C:28]([C:29]([NH:3][CH2:4][C:5]([N:7]2[CH2:12][CH2:11][N:10]([C:13]3[CH:18]=[C:17]([O:19][CH2:20][CH:21]([CH3:23])[CH3:22])[N:16]=[CH:15][N:14]=3)[CH2:9][CH2:8]2)=[O:6])=[O:30])=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 99734-Fluorobenzoic AcidHCID 66748304HCID 66748304, compound

Product 1

HCID 56654151HCID 56654151, compound

Procedure

The title compound was prepared according to the procedure described in Example 3 using 2-amino-1-(4-(6-isobutoxypyrimidin-4-yl)piperazin-1-yl)ethanone dihydrochloride and 4-fluorobenzoic acid.

Sources & evidence

ORD record
ord-2d814f7359e144fe8f2dbb03a8e6c929
Source dataset
uspto-grants-2015_04
Patent number
US08999974B2

Reaction notes

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