Piperazin-2-one → HCID 66748301, compound

HRID 1464970Notes

Reaction equation

HRID 1464970 reaction equation
Cl[C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH:10]([CH3:12])[CH3:11])[N:5]=[CH:4][N:3]=1.[NH:13]1[CH2:18][CH2:17][NH:16][CH2:15][C:14]1=[O:19]>>[CH2:9]([O:8][C:6]1[N:5]=[CH:4][N:3]=[C:2]([N:16]2[CH2:17][CH2:18][NH:13][C:14](=[O:19])[CH2:15]2)[CH:7]=1)[CH:10]([CH3:12])[CH3:11]

Participants

3

Reactant 2

HCID 231360Piperazin-2-oneHCID 61278956HCID 61278956, compound

Product 1

HCID 66748301HCID 66748301, compound

Procedure

The title compound was prepared according to the procedure described in Step 1 of intermediate C using 4-chloro-6-isobutoxypyrimidine and piperazin-2-one.

Sources & evidence

ORD record
ord-57e6aaf7fa49476c9e5969cf9aa3257c
Source dataset
uspto-grants-2015_04
Patent number
US08999974B2

Reaction notes

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