HCID 58505912, compound → HCID 66748334, compound

HRID 1464972Notes

Reaction equation

HRID 1464972 reaction equation
Cl.[CH2:2]([O:6][C:7]1[CH:12]=[C:11]([N:13]2[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]2)[N:10]=[CH:9][N:8]=1)[CH:3]([CH3:5])[CH3:4].[I:19][C:20]1[N:24]([CH3:25])[N:23]=[C:22]([C:26](O)=[O:27])[CH:21]=1>>[I:19][C:20]1[N:24]([CH3:25])[N:23]=[C:22]([C:26]([N:16]2[CH2:17][CH2:18][N:13]([C:11]3[CH:12]=[C:7]([O:6][CH2:2][CH:3]([CH3:5])[CH3:4])[N:8]=[CH:9][N:10]=3)[CH2:14][CH2:15]2)=[O:27])[CH:21]=1

Participants

3

Reactant 2

HCID 58505912HCID 58505912, compoundHCID 66748515HCID 66748515, compound

Product 1

HCID 66748334HCID 66748334, compound

Procedure

The title compound was prepared according to the procedure described in Example 3 using 4-isobutoxy-6-(piperazin-1-yl)pyrimidine hydrochloride and 5-iodo-1-methyl-1H-pyrazole-3-carboxylic acid.

Sources & evidence

ORD record
ord-ae44c57cdaf04887a62d9ee2640807e1
Source dataset
uspto-grants-2015_04
Patent number
US08999974B2

Reaction notes

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