4-(4-Ethylpiperazin-1-yl)aniline → HCID 53345320, compound

HRID 1464995Notes

Reaction equation

HRID 1464995 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:20])[NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:19])([F:18])[F:17])[CH:11]=2)=[CH:4][C:3]=1[NH:21][C:22]([C:24]1[C:28]2[N:29]=[CH:30][N:31]=[C:32](S(C)=O)[C:27]=2[S:26][CH:25]=1)=[O:23].[CH2:36]([N:38]1[CH2:43][CH2:42][N:41]([C:44]2[CH:50]=[CH:49][C:47]([NH2:48])=[CH:46][CH:45]=2)[CH2:40][CH2:39]1)[CH3:37]>>[CH2:36]([N:38]1[CH2:39][CH2:40][N:41]([C:44]2[CH:50]=[CH:49][C:47]([NH:48][C:32]3[C:27]4[S:26][CH:25]=[C:24]([C:22]([NH:21][C:3]5[CH:4]=[C:5]([C:8](=[O:20])[NH:9][C:10]6[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:19])([F:18])[F:17])[CH:11]=6)[CH:6]=[CH:7][C:2]=5[CH3:1])=[O:23])[C:28]=4[N:29]=[CH:30][N:31]=3)=[CH:46][CH:45]=2)[CH2:42][CH2:43]1)[CH3:37]

Participants

3

Reactant 2

HCID 9367384-(4-Ethylpiperazin-1-yl)anilineHCID 68263099HCID 68263099, compound

Product 1

HCID 53345320HCID 53345320, compound

Procedure

The procedure of Step 3 of Example 13 was repeated except for using the compound obtained in Step 2 of Example 13 and 4-(4-ethylpiperazine-1-yl)aniline to obtain the title compound (see Table 1).

Sources & evidence

ORD record
ord-8124667ce7194722b63e5e13983ecfd3
Source dataset
uspto-grants-2015_04
Patent number
US08999973B2

Reaction notes

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