Isopropylamine → HCID 53345206, compound

HRID 1464996Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:20])[NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:19])([F:18])[F:17])[CH:11]=2)=[CH:4][C:3]=1[NH:21][C:22]([C:24]1[C:28]2[N:29]=[CH:30][N:31]=[C:32](S(C)=O)[C:27]=2[S:26][CH:25]=1)=[O:23].[CH:36]([NH2:39])([CH3:38])[CH3:37]>>[CH:36]([NH:39][C:32]1[C:27]2[S:26][CH:25]=[C:24]([C:22]([NH:21][C:3]3[CH:4]=[C:5]([C:8](=[O:20])[NH:9][C:10]4[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:19])([F:17])[F:18])[CH:11]=4)[CH:6]=[CH:7][C:2]=3[CH3:1])=[O:23])[C:28]=2[N:29]=[CH:30][N:31]=1)([CH3:38])[CH3:37]

Participants

Reactant 2

HCID 6363Isopropylamine

HCID 68263099HCID 68263099, compound

Product 1

HCID 53345206HCID 53345206, compound

Procedure

The procedure of Step 3 of Example 13 was repeated except for using the compound obtained in Step 2 of Example 13 and isopropylamine to obtain the title compound (see Table 1).

Sources & evidence

ORD record: ord-266c1f3e36034d4da23a236be8374b6c
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08999973B2

Reaction notes

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