反应详情

温度

70 °C

(4-Chlorothieno[3,2-d]pyrimidine-7-yl)methanol (215 mg, 0.99 mmol) and MnO2 (863 mg, 9.9 mmol, 10 eq) were dissolved in chloroform (10 mL) and stirred at 70° C. for 2 hours. The reaction mixture was cooled to room temperature, filtered with Celite and concentrated to obtain the title compound as a white solid without further purification.

1. temperatureThe reaction mixture was cooled to room temperature
2. filtrationfiltered with Celite
3. concentrationconcentrated