HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Fluoronitrobenzene → 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Fluoronitrobenzene | HCID 9590 | — |
| Reactant | HCID 178486804 | HCID 178486804 | — |
| Product | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline | HCID 11594543 | — |
Reaction Steps
L1 was prepared from 6,7-dimethoxyquinolin-4-ol and 4-fluoro-nitrobenzene following the general procedure reported in Preparative Example 1 Step 1-2. 1H NMR (400 MHz, d6-DMSO, 300K) δ 3.91 (s, 3H), 3.92 (s, 3H), 5.16 (br s, 2H), 6.36 (d, J=5.3 Hz, 1H), 6.65 (d, J=8.8 Hz, 2H), 6.91 (d, J=8.8 Hz, 2H), 7.34 (s, 1H), 7.49 (s, 1H), 8.41 (d, J=5.3 Hz, 1H). MS (ES) C17H16N2O3 requires: 296. Found: 297 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999982B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-1fa6af77a0114be7aa38840b88051279 |
| Source note | uspto-grants-2015_04 |