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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1465285Generated: November 1, 2026

2-Methyl-5-vinylpyridine → HCID 57876131, compound

https://huagongshe.com/reaction/1465285

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-vinylpyridineHCID 8817—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 68757772HCID 68757772—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 57876131HCID 57876131—

Reaction Steps

The title compound is prepared from a mixture of 2-(4-bromophenyl)-2,3,4,5-tetrahydro-8-methyl-1H-pyrido[4,3-b]indole, 2-methyl-5-vinylpyridine and KOH (5-7 equiv) in NMP at a temperature ranging between 25 deg C. to 100 deg C. The product obtained is isolated by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08999978B2
Source datasetuspto-grants-2015_04
ORD IDord-0d3cb24cddf946d0ab186bdb5255c471
Source noteuspto-grants-2015_04