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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1465301Generated: October 27, 2026

1-Methyl-4-piperidone → 5-(4-fluorophenethyl)-6-chloro-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indole

https://huagongshe.com/reaction/1465301

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-4-piperidoneHCID 74049—
Reactant2-Chlorophenylhydrazine hydrochlorideHCID 443287—
Reactant4-Fluorophenethyl bromideHCID 573153—
SolventTriethylamineHCID 8471—
Product5-(4-fluorophenethyl)-6-chloro-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indoleHCID 57876351—

Reaction Steps

The title compound is prepared by following Method 8 by using 1-(2-bromoethyl)-4-fluorobenzene, 2-chlorophenylhydrazine hydrochloride, triethylamine and N-methyl-4-piperidone

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08999978B2
Source datasetuspto-grants-2015_04
ORD IDord-6ab92bb800614b0dab1fdc2fa945bde8
Source noteuspto-grants-2015_04