HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-5-vinylpyridine → HCID 57876060, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-5-vinylpyridine | HCID 8817 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 68929116 | HCID 68929116 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 57876060 | HCID 57876060 | — |
Reaction Steps
The title compound is prepared from a mixture of 3,4-dihydro-3-hydroxy-2,8-dimethyl-2H-pyrido[4,3-b]indol-1(5H)-one, 2-methyl-5-vinylpyridine and KOH (5-7 equiv) in NMP at a temperature ranging between 25 deg C. to 100 deg C. The product obtained is isolated by preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999978B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-65bb2086c10e4fa9959ef39bf90290b4 |
| Source note | uspto-grants-2015_04 |