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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1465435Generated: October 25, 2026

Ethyl 2-(4-bromophenoxy)acetate → 2-(4-Bromophenoxy)acetamide

https://huagongshe.com/reaction/1465435

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(4-bromophenoxy)acetateHCID 248825—
ReactantAmmonia methanolHCID 21705897—
Product2-(4-Bromophenoxy)acetamideHCID 30286498%

Reaction Steps

7M-Ammonia methanol solution (10 ml, 70 mmol) was added to ethyl 2-(4-bromophenoxy)acetate (1.0 g, 3.86 mmol), and the mixture was stirred at room temperature for 2.5 hrs. The reaction mixture was concentrated under reduced pressure to give 2-(4-bromophenoxy)acetamide (870 mg, yield 98%) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08999989B2
Source datasetuspto-grants-2015_04
ORD IDord-0474a42cf25b40b6b4b1e58b784d031d
Source noteuspto-grants-2015_04